Official Site of The State of New Jersey
Down Syndrome (Trisomy 21) by Year, New Jersey, 2000 to 2022
Indicator Report Data View Options
Why Is This Important?
Trisomy 21 (Down syndrome) is a chromosomal abnormality characterized by the presence of an extra copy of the 21st chromosome. Down syndrome is the most frequent genetic condition of childhood associated with mental retardation.
Maternal age is a major risk factor that increases the chance of conceiving a baby with Down syndrome. At maternal age 20 to 24, the probability of conceiving a child with Down Syndrome is 1 in 1,562; at age 35 to 39 the probability increases to 1 in 214; and above age 45 the probability increases to 1 in 19. However, though the probability of a child being born with Down syndrome increases with maternal age, approximately 80% of children with Down syndrome are born to women under the age of 35. There are currently no known environmental factors that are associated with developing Down syndrome.
Definition
Number of children born with Down syndrome per 10,000 live births to women residing in New Jersey in a specified time interval.
Data Sources
- Birth Certificate Database, Office of Vital Statistics and Registry, New Jersey Department of Health
(https://www.nj.gov/health/vital/) - Early Identification and Monitoring Program, Division of Family Health Services, New Jersey Department of Health
(https://www.nj.gov/health/fhs/eis/)
How the Measure is Calculated
Numerator:
Number of children born with Down syndrome among live births to women residing in New Jersey in a specified time interval.Denominator:
Count of all live births to women residing in New Jersey in a specified time interval.
Related Health Objectives and Indicators
Environmental Public Health Tracking Indicator BD-12
Description: Prevalence of Down syndromehttps://ephtracking.cdc.gov/indicatorPages?selectedContentAreaAbbreviation=5&selectedIndicatorId=12